Front Row (left to right): Kristy Rose; Coco Kang; Dr Priyanka Bandara;
Paula Bray.
Back Row (left to right): Dr Joshua Burns.

The clinical research program at the INMR is aimed to identify new treatments for inherited and acquired nerve and muscle disorders of childhood.

To reach this aim a number of clinical trials and long term studies of natural history are being conducted with people who volunteer to take part. Carefully conducted clinical trials are the fastest and safest way to find treatments that work and ways to improve health.

Each study answers specific scientific questions and tries to find better ways to prevent, screen for, diagnose, or treat a disease. Current research studies at the INMR include:

Peripheral Neuropathy

• Australasian Paediatric Charcot-Marie-Tooth disease Registry

• Ascorbic Acid therapy for Charcot-Marie-Tooth disease type 1A

• Critical illness polyneuropathy in children

• Night casting for ankle contracture in Charcot-Marie-Tooth disease

• Management of the cavus foot deformity with botulinum toxin A

• Foot surgery in children with Charcot-Marie-Tooth disease

• Footwear and orthotic management of Charcot-Marie-Tooth disease

• Investigation of the neuronal types of Charcot-Marie-Tooth disease in children

Muscular Dystrophy

• Quality of life in boys with Duchenne Muscular Dystrophy

• New steroid and other treatments for Duchenne muscular dystrophy

• Disease modifying genes in muscle disease

These studies are being undertaken at CHW singly or in collaboration with internationally-based clinical trials groups including the Cooperative International Neuromuscular Research Group (CINRG), which is based in Washington DC, and the European Neuromuscular Centre neuromuscular research consortium.